Evaluation of anti-inflammatory and analgesic activity from Vitexnegundo Linn

ShambaleedHumayun*, Muhammad Ibrar

Department of Botany, University of Peshawar, Pakistan

Key words: Analgesic, anti-inflammatory, phytochemical, Vitexnegundo Linn.

vitex-negundoAbstract

Analgesic and anti-inflammatory activity along with phytochemical screening was carried out on leaf ethanolic extract of Vitexnegundo Linn. Phytochemical screening has shown presence of various phytochemicals like carbohydrates, proteins, triterpenoids, calcium oxalate, volatile oils, starch, saponin, flavonoides and tannins. Analgesic activity was carried out by using two models (acetic acid model and tail immersion model). Acetic acid model showed significant effects whereas tail immersion model showed non-significant results which mean that the analgesic effects of Vitexnegundo is “orally controlled”. Anti-inflammatory activity shows significant results. On the basis of present study it can be suggested that this plant has great potentials as a good and cheap source for anti-inflammatory and analgesic drugs preparations. Further investigation is required to evaluate the therapeutic properties of the plant.

Get the original articles in Source: Volume 4, Number 1, January 2014 – JBES

Published By:  Journal of Biodiversity and Environmental Sciences (JBES)

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